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DNA Sequence Compression
Friedrich, Tomáš ; Burgetová, Ivana (referee) ; Martínek, Tomáš (advisor)
The increasing volume of biological data requires finding new ways to save these data in genetic banks. The target of this work is design and implementation of a novel algorithm for compression of DNA sequences. The algorithm is based on aligning DNA sequences agains a reference sequence and storing only diferencies between sequence and reference model. The work contains basic prerequisities from molecular biology which are needed for understanding of algorithm details. Next aligment algorithms and common compress schemes suitable for storing of diferencies agains reference sequence are described. The work continues with a description of implementation, which is follewed by derivation of time and space complexity and comparison with common compression algorithms. Further continuation of this thesis is discussed in conclusion.
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DNA Sequence Compression
Friedrich, Tomáš ; Burgetová, Ivana (referee) ; Martínek, Tomáš (advisor)
The increasing volume of biological data requires finding new ways to save these data in genetic banks. The target of this work is design and implementation of a novel algorithm for compression of DNA sequences. The algorithm is based on aligning DNA sequences agains a reference sequence and storing only diferencies between sequence and reference model. The work contains basic prerequisities from molecular biology which are needed for understanding of algorithm details. Next aligment algorithms and common compress schemes suitable for storing of diferencies agains reference sequence are described. The work continues with a description of implementation, which is follewed by derivation of time and space complexity and comparison with common compression algorithms. Further continuation of this thesis is discussed in conclusion.
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Decision-making about cloud service providers with respect to data security
Račanský, Jan ; Matuštík, Ondřej (advisor) ; Böhmová, Lucie (referee)
Organizations that during the past years become accustomed to run its services on its on-premise solution, have increasingly to decide if they will in these days continue to operate their IT services in this way, or take advantage of new opportunities for cloud-based solution. However, the transition to this new technology, which entrusts their data into the hands of external companies, accompanied by a fear of security of their sensitive data. The main objective of this thesis is to propose a reference model that will assist organizations in their selection process of cloud service providers with respect to data security. In conclusion the quality and usefulness of this reference model is validated by knowledge and information, which are obtained during interviews with IT specialists.
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Implementation of ECM solutions in tasks of corporate governance
Herold, Radek ; Pour, Jan (advisor) ; Hrbáček, David (referee)
The work is focused on ECM and representation in the reference model of IT management MBI. The primary objective is to expand and update ECM components in the MBI as objects, tasks which are represented as the business processes related to IT management and the relationships between these objects and tasks. Work provides an detailed overview of the benefits, risks and problems associated with the implementation of the various components of ECM.
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IS/ICT sourcing strategies in healthcare facilities
Potančok, Martin ; Voříšek, Jiří (advisor) ; Pour, Jan (referee) ; Šalamon, Tomáš (referee) ; Vejvodová, Jiřina (referee)
The dissertation thesis focuses on information systems and communication technologies and ways they are provided (sourced) in healthcare. The aim of this dissertation thesis is to design and verify a model of IS/ICT sourcing strategy for healthcare as a factor leading to the improvement of patient care, taking into account different categories of healthcare facilities and other specifics resulting from the application in medicine. The introductory section of the thesis (Section A) defines the areas of health care and identifies their specifics. Moreover, categories of healthcare facilities are defined and therapeutic, nursing and IS/ICT processes are identified. Sourcing is defined for the needs of the designed sourcing strategy model and the current trends are analysed as well as the offered outsourcing services. In the next section of the thesis (Section B), requirements on the IS/ICT sourcing strategy model are defined. Theories of sourcing strategies are analysed including assessment of the current practices of healthcare facilities. Identification of specific factors affecting sourcing in healthcare is an essential part of this section. The most important section of the thesis is a design of the IS/ICT sourcing strategy model and its verification in practice at a real healthcare facility, which is described in the final part (Section C). The designed model employs two layers to cover the whole spectrum of healthcare facilities. The base layer defines the types of objects used in developing the sourcing strategy. The specific layer takes into consideration the differences between the various categories of healthcare facilities and provides the actual implementation. Successful implementation of the model including its two layers was achieved in an independent outpatient healthcare facility.
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The reference model of marketing support processes and its evaluation
Vydra, Pavel ; Oškrdal, Václav (advisor) ; Hornická, Andrea (referee)
Corporate expenses for IT support of marketing are surging every year, and therefore the processes of marketing support, which contain all the technical aspects of marketing campaign execution and measurement, are attracting more attention than before. The diploma thesis introduces a basic overview of direct marketing and marketing support operations in corporations and presents a reference model to help optimize the marketing support processes. The thesis contains a research of theoretical fundamentals of process modelling and reference model building, a basic overview of corporate direct marketing, an analysis of direct marketing processes and the most relevant processes of marketing support. The reference model, which is based on the outputs from both theoretical parts, includes a detailed description of marketing support processes and outlines the process boundaries in the form of SLA. The model is then tested on two case studies, which emphasize the practical opportunities as well as the major benefits of using the model.
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Financial Management for Business in the Management of Business Informatics (MBI) model
Klouček, Ondřej ; Pour, Jan (advisor) ; Štefaňák, Vladislav (referee)
This diploma thesis focuses on two individual tasks in the MBI model (Management Business of Informatics). Analyzed tasks come under the section of Business Information System, specifically under the Business Financial Management group of tasks. The tasks deal with financial analysis, financial planning and budgets. The aim of the thesis is to create these tasks sufficiently detailed for the MBI model including detailed elaboration of the key activities and linkages to the existing MBI environment. The theoretical part consists of analysis of information sources. The practical part is based on these theoretical findings, which are grouped into logical units and, based on the assessment of the current state, remodeled into the form compliant with the MBI rules. The author of the thesis contributed to this research subject with creating the above mentioned tasks, including detailed key activities and with analysis and the blueprint of the linkages of the newly created tasks to the existing content of MBI in order to ensure effective work with the model for the users. Model documents and templates for calculations have been created for some of the tasks. The first part of the thesis theoretically describes the research subject with a focus on the systems of source information for the analyzed tasks. Based on this theoretical part, the practical part contains the commented version of tasks for the MBI model including the linkages for other methodical objects and contingent model materials.
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Management of ECM within ICT management model MBI
Malý, Jan ; Pour, Jan (advisor) ; Pražský, Petr (referee)
The thesis is focused on ECM and its representation in the reference model of IT management MBI. The main objective is to extend the aforementioned model with objects associated with the ECM - factors describing the structure of solutions, tasks defining the procedure for its implementation and the links between them and existing objects. The thesis analyzes in detail the benefits, but also the risks and problems associated with solution implementation. The methodology provides a set of best practices for the implementation of ECM.
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The relationship between the EA and selected reference models
Příhoda, Stanislav ; Chlapek, Dušan (advisor) ; Buchalcevová, Alena (referee)
This thesis is focused on the competence of Enterprise Architecture, which is discussed in the introductory theoretical part as a comprehensive practice and subsequently in the relation between Enterprise Architecture and a specific aspect that is used in the EA initiatives - the reference models is discussed. In relation to the set objective the basic definitions of Enterprise Architecture are discussed and analyzed in the Chapter 2, and brief look at the description of the architectures along with the key business drivers and benefits of EA is also provided. In the Chapter 3 the content evolution of architectural disciplines is presented, particularly in terms of the scope of EA and maturity in the enterprises. A general analysis of the Enterprise Architecture is completed in the Chapter 4 where is addressed a crucial aspect of Enterprise Architecture - the architectural frameworks. The second part focuses on the key objectives of the thesis related to the reference models. The criterial evaluation system of reference models and the classification scheme for reference models are introduced as the key proposed approaches. In chapter 5.3 is also provided the structural analysis of five selected reference models that are evaluated on the basis of the predefined criteria and classified in the proposed scheme at the end. Both proposed approaches, the criterial evaluation system and the classification scheme for reference models, are in the chapter 5.6 assessed and verified by the subject matter experts in the field of EA.
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